Garlic attenuates cardiac oxidative stress via activation of PI3K/AKT/Nrf2-Keap1 pathway in fructose-fed diabetic rat.
BackgroundCardiovascular complication due to diabetes has remained a major cause of death.There is an urgent need to intervene the cardiac complications in diabetes by nutritional or pharmacological agents.Thus the present study was designed to find out the effectiveness of garlic on cardiac complications in insulin-resistant diabetic rats.Methods